https://ogma.newcastle.edu.au/vital/access/ /manager/Index en-au 5 https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:51338 Wed 13 Mar 2024 14:06:52 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:4493 Wed 11 Apr 2018 10:59:49 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:43939 Wed 05 Oct 2022 12:51:37 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:53453 Tue 28 Nov 2023 10:10:54 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:39873 Tue 28 Jun 2022 14:40:02 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:33554 Tue 04 Jun 2019 15:39:56 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:51330 Thu 31 Aug 2023 15:36:50 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:41180 Thu 28 Jul 2022 10:58:19 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:7386 Sat 24 Mar 2018 11:13:39 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:47 Sat 24 Mar 2018 07:42:00 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:22863 IL-1beta-511C/T polymorphism and smoking behavior in schizophrenia versus healthy controls in a Chinese population. The IL-1beta-511C/T polymorphism was genotyped in 638 male patients with chronic schizophrenia (smoker/never-smoker=486/152) and 469 male controls (smoker/never-smoker=243/226). The cigarettes smoked per day, the Heaviness of Smoking Index (HSI) and the Fagerstrom Test for nicotine dependence (FTND) were assessed. Patients were also rated on the Positive and Negative Syndrome Scale (PANSS). The results showed no significant differences in genotype and allele distribution between patients and controls, and between smokers and never-smokers in either the patient or control group. However, in patients, smokers with the C/C genotype had significantly higher HSI (p<0.005) and FTND (p<0.05) scores than smokers with the T/T genotype, without significant differences in controls. Furthermore, there was a linear positive correlation between the number of C alleles and the HSI (p<0.005) in patients. Our findings suggest that the IL-1beta-511C/T polymorphism may not be related to schizophrenia or smoking status in Chinese individuals, but may affect the severity of nicotine dependence among male smokers with schizophrenia.]]> Sat 24 Mar 2018 07:16:01 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:49500 Fri 19 May 2023 12:08:56 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:53838 5-10 cigarettes per day. Animal studies investigated kidney histopathology and highlighted kidney injury and microscopic changes in response to nicotine exposure during pregnancy. Further research is required to determine the impact on kidney function. Recreational nicotine use is evolving, and with the increasing use of urine cotinine in the evaluation of nicotine exposure, further research is needed.]]> Fri 19 Jan 2024 10:11:37 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:49952 Fri 16 Jun 2023 13:49:41 AEST ]]>